Safety, quality & education

Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index*

Crit Care MedPublished Retrospective cohort study

Main finding · In-hospital mortalityResult — go to the resultOdds ratio 1.49 99% CI 1.38–1.60

Authors' conclusion

The Activity index is a simple and valid measure that identifies ICUs in which increasing strain leads to progressively worse patient outcomes.

Study context

Population
Adult ICU patients, 175 public and private hospitals in Australia (June 2020 through March 2022)
Participants
277,737 patients · 175 hospitals
Exposure
ICU stay during time-periods with higher vs lower Activity index
Outcome
In-hospital mortality
Methodological detailsnational registry-based
  • National registry-based

Main finding

As reported in the abstract

Odds ratio

1.49

99% CI 1.38–1.60

By group

ICU stay during time-periods with higher vs lower Activity index
OR 1.49 (99% CI 1.38–1.60)
Overall in-hospital deaths
19,177 (6.9%)

Observational data: associations, not effects.

Secondary outcomes

After-hours ICU discharge

OR (99% CI)
Higher Activity indicesAdjusted for confounders1.27 (1.21–1.34)

ICU readmission

OR (99% CI)
Higher Activity indicesAdjusted for confounders1.18 (1.09–1.28)

Interhospital transfer to another ICU

OR (99% CI)
Higher Activity indicesAdjusted for confounders1.92 (1.72–2.15)

Delay in ICU discharge

OR (99% CI)
Higher Activity indicesAdjusted for confounders; less delay0.58 (0.55–0.62)

Activity index during ICU stay

Median Activity index (IQR 0.40-1.24)
0.87

Original publication

Measuring the Impact of ICU Strain on Mortality, After-Hours Discharge, Discharge Delay, Interhospital Transfer, and Readmission in Australia With the Activity Index*. Crit Care Med. Published 24 July 2023. doi:10.1097/ccm.0000000000005985

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