Cardiac arrest & resuscitation
Measuring transient return of spontaneous circulation and rearrest after in-hospital cardiac arrest: a prospective validation study
Authors' conclusion
This validation study supports the use of a 60-s waveform-derived definition of transient ROSC with high accuracy compared to in-person identification.
Study context
- Population
- IHCA cases with retrievable defibrillator waveform data, large metropolitan hospital system, April 2025 to January 202634 (71%) included
- Participants
- 48 cases
- Comparison
- 60-s waveform-derived definition vs Directly observed standard
- Outcome
- Accuracy (sensitivity, specificity, PPV, NPV) of the 60-s waveform-derived definition for transient ROSC vs direct observation, patient- and event-level
Methodological detailsprospective validation, convenience sample, blinded waveform review
- Prospective validation
- Convenience sample
- Blinded waveform review
Performance
As reported in the abstract
Transient ROSC identification
| Test or model | Sensitivity (patient level) | Specificity (patient level) | PPV (patient level) | NPV (patient level) | Sensitivity (event level) | PPV (event level) | False positives (event level) |
|---|---|---|---|---|---|---|---|
| 60-s waveform-derived definition | 100% | 100% | 100% | 100% | 86% (18/21) | 18/20, 90% | 2 |
60-s waveform-derived definition
Sensitivity (patient level)100%
Specificity (patient level)100%
PPV (patient level)100%
NPV (patient level)100%
Sensitivity (event level)86% (18/21)
PPV (event level)18/20, 90%
False positives (event level)2
Further findings
Patients with ≥1 directly observed transient return of spontaneous circulation (ROSC) event (prevalence)
- Patients with at least one directly observed transient ROSC event, of 34 included
- 13 (38%)
Original publication
Measuring transient return of spontaneous circulation and rearrest after in-hospital cardiac arrest: a prospective validation study. Resuscitation. Published 20 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →