Airway management

Narrative Review of Prolonged Times to Tracheal Extubation After General Anesthesia With Intubation and Extubation in the Operating Room

Anesth AnalgPublished Narrative review

Authors' conclusion

Collectively, the results show that when investigators in anesthesia pharmacology quantify the rate of patient recovery from general anesthesia, the incidence of prolonged times to tracheal extubation should be included as a study end point.

Study context

Population
Patients after GA with tracheal intubation and extubation in the OR or other anesthetizing location
Outcome
Prolonged times to tracheal extubation (>15 minutes or at least 15 minutes)

Main finding

As reported in the abstract

  • Prolonged times to extubation can be measured accurately
  • Associated with reintubations and respiratory treatments
  • Rated poorly by anesthesiologists; treated with flumazenil and naloxone
  • Associated with impaired OR workflow, longer OR times, tardiness of starts of to-follow cases and surgeons, and longer workdays
  • Covariates accounting for most prolonged extubations: characteristics of the surgery, positioning, and anesthesia provider's familiarity with the surgeon
  • Anesthetic drugs and delivery systems routinely achieve substantial differences in the incidences of prolonged extubations
  • Benefits of different anesthetics achieved principally by reducing variability in extubation times (decreasing incidence of prolonged extubations), not shown by medians and means
  • Literature search current through May 2023

Original publication

Narrative Review of Prolonged Times to Tracheal Extubation After General Anesthesia With Intubation and Extubation in the Operating Room. Anesth Analg. Published 3 October 2023. doi:10.1213/ane.0000000000006644

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