ICU sedation, delirium & recovery
Nurse-led family participatory support intervention on clinical outcomes in intensive care units (ICU) patients: a prospective quasi-experimental study
Authors' conclusion
The NFPS significantly reduced the incidence of delirium and was associated with shorter durations of mechanical ventilation, ICU-LOS, HLOS, lower hospitalization costs, without increasing the risks of ICU-AW, ICU-acquired infection, or adverse events.
Study context
- Population
- Adult ICU patients from three tertiary hospitals in Gansu Provincepropensity-matched
- Participants
- 365 vs 365
- Exposure
- NFPS vs non-NFPS
- NFPSn = 365
- non-NFPSn = 365reference
- Outcome
- Incidence of delirium
Methodological details1:1 propensity score matching, multicentre (three tertiary hospitals)
- 1:1 propensity score matching
- Multicentre (three tertiary hospitals)
Main finding
As reported in the abstract
P = 0.03
Observational data: associations, not effects.
Further findings
Hospital LOS
P < 0.001
ICU-LOS
P < 0.001
Duration of mechanical ventilation
P < 0.001
Hospitalization cost
P = 0.032
6-month mortality
- No significant difference (6.03% vs. 7.67%, P = 0.380)
1-year mortality
- No significant difference (9.32% vs. 11.51%, P = 0.330)
Safety
ICU-acquired weakness
- No significant difference (26.58% vs. 29.59%, P = 0.270)
ICU-acquired infection
- No significant difference (19.45% vs. 19.73%, P = 0.930)
Adverse events
- No significant difference (2.19% vs. 3.84%, P = 0.190)
Original publication
Nurse-led family participatory support intervention on clinical outcomes in ICU patients: a prospective quasi-experimental study. Crit Care. Published 18 June 2026. doi:10.
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