Pain medicine

Opioid administration across racial and ethnic groups for patients undergoing liver resection: are there disparities?

Perioper Med (Lond)Published Retrospective cohort study

Authors' conclusion

For patients undergoing liver resection surgery, no racial and ethnic disparities were observed for weight-based intraoperative MME.

Study context

Population
Adults undergoing open liver resection, January 2012 to May 2019
Participants
1,294 open liver resections
Exposure
Racial and ethnic groups
  • Whiten = 532reference
  • Asiann = 401
  • Blackn = 159
  • Hispanicn = 97
  • Othern = 105
Outcome
Weight-based intraoperative MME (MME/kg)
Methodological detailssingle-centre, multivariable regression
  • Single-centre
  • Multivariable regression

Main finding

As reported in the abstract

Risk-adjusted mean intraoperative MME/kg

Asian vs White: P = 0.87 · Black vs White: P = 0.19 · Hispanic vs White: P = 0.97

Observational data: associations, not effects.

Secondary outcomes

OutcomeEstimate (CI)P value
LOSBlack vs White · multivariable model1.17 (1.00–1.35)P = 0.047
LOSHispanic vs White · multivariable model1.30 (1.05–1.65)P = 0.018

Length of stay (LOS)

LOS significantly higher for Black and Hispanic vs White

Receipt of regional anaesthesia

No racial/ethnic group significantly associated with higher or lower odds

Original publication

Opioid administration across racial and ethnic groups for patients undergoing liver resection: are there disparities? Perioper Med (Lond). Published 2 December 2024. doi:10.1186/s13741-024-00473-w

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