Cardiac arrest & resuscitation
Out-of-hospital cardiac arrest survival when cardiopulmonary resuscitation (CPR) is initiated by first responders
Authors' conclusion
CPR initiated by first responders for OHCA is associated with higher overall survival rates and higher survival was largely mediated by earlier response times.
Study context
- Population
- Adults with non-traumatic out-of-hospital cardiac arrest (OHCA) in whom CPR was initiated by first responders or emergency medical service (EMS), CARES registry, 2013–2021
- Participants
- 162,896 adults
- Exposure
- CPR initiated by first responders vs EMS
- First respondersn = 70,889
- EMSn = 92,007reference
- Outcome
- Survival to hospital admission and to discharge
Methodological detailsregistry-based (CARES), multivariable hierarchical logistic regression
- Registry-based (CARES)
- Multivariable hierarchical logistic regression
Main finding
As reported in the abstract
First responders
- Survival to hospital admission
- 27.1%
- Survival to discharge
- 9.4%
EMS
- Survival to hospital admission
- 26.8%
- Survival to discharge
- 7.7%
Survival to hospital admission
First responders27.1%
EMS26.8%
Survival to discharge
First responders9.4%
EMS7.7%
First responders vs EMSAdjusted odds ratio (CI)P value
Survival to hospital admission
0.98(0.96–1.01)
P = 0.15Survival to discharge
1.17(1.02–1.21)
P < 0.001Observational data: associations, not effects.
Further findings
Time to first CPR
standardized difference 16.1%
| Outcome | Adjusted OR (CI) | P value | |
|---|---|---|---|
| Survival to discharge, additionally adjusted for time to first CPR | 1.04 (1.00–1.08) | P = 0.07 | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Out-of-hospital cardiac arrest survival when CPR is initiated by first responders. Resuscitation. Published 26 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →