ICU sedation, delirium & recovery

Outcome and factors associated with mortality in patients receiving urgent chemotherapy in the intensive care unit (ICU): A retrospective study

J Crit CarePublished Retrospective cohort study

Authors' conclusion

Urgent CT in the ICU is feasible in a specific subset of patients, mainly those with hematological cancer, with resumption of the curative treatment regimen after ICU discharge.

Study context

Population
Adults with cancer requiring urgent chemotherapy during ICU stay, Lyon, France, October 2014–December 2019
Participants
147 adults
Outcome
Mortality
Follow-up
6 months
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

6-month mortality

6-month mortality rate

69.4%

Observational data: associations, not effects.

Further findings

Patient characteristics

Hematological cancer
77%
Acute respiratory failure as leading cause of ICU admission
46.3%

Resumption of conventional chemotherapy (CT) among ICU survivors

Resumed conventional CT
95%
Higher likelihood of resuming CT with hematological cancer

Original publication

Outcome and factors associated with mortality in patients receiving urgent chemotherapy in the ICU: A retrospective study. J Crit Care. Published 7 August 2023. doi:10.1016/j.jcrc.2023.154399

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