Cardiac arrest & resuscitation

Outcome of comatose patients following cardiac arrest: When modified Rankin Scale (mRS) completes Cerebral Performance Category (CPC)

ResuscitationPublished Prospective cohort study

Authors' conclusion

CPC and mRS correlate similarly with neuronal damage. Whilst CPC 1-2 and CPC 4-5 are strongly associated with mRS 0-3 and, respectively, with mRS 5-6, CPC 3 is heterogenous: both good and poor mRS scores are found within this category.

Study context

Population
Comatose adults after cardiac arrest, treated April 2016–April 2023
Participants
665 adults
Outcome
mRS within each CPC category; correlation of peak NSE (first 48 h) with CPC and mRS
Follow-up
3 months
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

CPC 3: good outcome (mRS 0-3)

53.1%

CPC 3: poor outcome (mRS 4-6)

46.9%

Neuron specific enolase (NSE) correlation with CPC (Spearman's rho; P < 0.001)

0.616

NSE correlation with mRS (Spearman's rho; P < 0.001)

0.613

Observational data: associations, not effects.

Original publication

Outcome of comatose patients following cardiac arrest: When mRS completes CPC. Resuscitation. Published 10 October 2023. doi:10.1016/j.resuscitation.2023.109997

Composed by AI from the published abstract and checked against it. How Briefs are made →

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