Outcomes after extracorporeal cardiopulmonary resuscitation in pediatric in-hospital cardiac arrest: does quality of CPR matter?
Authors' conclusion
While adherence to AHA guideline-complaint CPR was not significantly associated with SHD, patient age and CPR duration were significant predictors.
Study context
- Population
- Children (<18 years) with IHCA requiring ECMO to achieve ROSC (ECPR), 20 sites
- Participants
- 157 index ECPR events
- Exposure
- Guideline-compliant vs non-compliant CPR
- Outcome
- Survival to hospital discharge (SHD)
Methodological detailsmulticentre registry (PediRES-Q)
- Multicentre registry (PediRES-Q)
Main finding
As reported in the abstract
SHD by guideline compliance
- Guideline compliance not significantly associated with survival to hospital discharge (SHD) after adjusted logistic regression
- Adjusted for age, arterial line, CPR duration, clustering by site
Observational data: associations, not effects.
Further findings
Overall guideline compliance by age group · overall compliance was poor across age groups
| Outcome | aOR (CI) | P value | |
|---|---|---|---|
| SHD by age8-<18 years vs < 8 year · 64% lower odds of SHD · adjusted logistic regression | 0.36 (0.17–0.76) | P = 0.007 | |
| SHD by duration of CPR (every minute increase)Decreased survival odds by 2% · adjusted logistic regression | 0.98 (0.96,1.0) | P = 0.02 | |
| 0.10.31310Adjusted odds ratio (log scale) |
Original publication
Outcomes after extracorporeal cardiopulmonary resuscitation in pediatric in-hospital cardiac arrest: does quality of CPR matter? Resuscitation. Published 7 April 2025. doi:10.
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