ICU sedation, delirium & recovery
Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis
Pooled result · Overall mortalityResult — go to the resultRelative risk 0.78 95% CI 0.62–0.98Authors' conclusion
In critically ill patients, the use of oXiris® membrane was associated with reduced overall mortality, norepinephrine dosage, CRP, IL-6, lactate levels, along with improved organ function.
Study context
- Population
- Critically ill adult patients10 studies (2 randomised controlled trials (RCTs), 8 non-randomised studies of intervention (NRSIs))
- Participants
- 481 patients
- Comparison
- Extracorporeal blood purification with oXiris® membrane vs comparator
- Outcome
- Overall mortality
Methodological detailsrandom effect meta-analyses
- Random effect meta-analyses
Pooled result
As reported in the abstract
Relative risk
0.78
95% CI 0.62–0.98
P = 0.03
Extracorporeal blood purification with oXiris® membrane vs comparator
RR 0.78 (95% CI 0.62–0.98); P = 0.03
Further pooled results
28-day mortality (1 RCT)
- No significant difference between groups
SOFA scores, norepinephrine dosage, CRP, lactate, IL-6 (pooled NRSIs) · post oXiris® treatment
- Significant reductions
ICU and hospital LOS, mechanical ventilation duration
- Similar between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis. J Crit Care. Published 19 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →