Pediatric anesthesia & critical care
Oxygenation during general anesthesia in pediatric patients: A retrospective observational study
Authors' conclusion
Oxygen administration during general pediatric anesthesia is barely regulated. Hyperoxemia is observed intraoperatively in approximately 90% of cases.
Study context
- Population
- Patients aged 0–18 years under GA with tracheal intubation and an arterial catheter, excluding CPB, June 2017 to August 2020645 samples analysed
- Participants
- 226 patients
- Outcome
- FiO2, PaO2 and SpO2 values; correlation between PaO2 and FiO2 (weighted Spearman correlation coefficient)
Methodological detailssingle-centre, tertiary pediatric academic hospital
- Single-centre
- Tertiary pediatric academic hospital
Main finding
As reported in the abstract
- FiO2, median (IQR 31 to 43; range 20% to 97%)
- 36%
- PaO2, median (IQR 18.6 to 28.1 kPa; 140 to 211 mmHg)
- 23.6 kPa; 177 mmHg
- SpO2, median (IQR 98 to 100%)
- 99%
- Moderately positive association between PaO2 and FiO2 (p < 0.001)
- r = 0.52
- Samples with PaO2 higher than 13.3 kPa; 100 mmHg (574 of 645)
- 89%
Observational data: associations, not effects.
Original publication
Oxygenation during general anesthesia in pediatric patients: A retrospective observational study. J Clin Anesth. Published 6 February 2024. doi:10.
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