Pain medicine

Pain after combat injury in male UK military personnel deployed to Afghanistan

Br J AnaesthPublished Cohort study

Main finding · Moderate or severe painResult — go to the resultRelative risk 1.1 95% CI 1.0–1.2

Authors' conclusion

Combat injury, but not amputation, was associated with a higher frequency of moderate to severe pain intensity in this cohort, and pain was associated with adverse mental health outcomes.

Study context

Population
Male UK armed forces personnel deployed to Afghanistan, ADVANCE cohort161 with amputations
Participants
579 vs 565
Exposure
Injured vs Uninjured
  • Injuredn = 579
  • Uninjuredn = 565reference
Outcome
Moderate or severe 'overall' pain intensity (self-reported)
Follow-up
Median 8 yr since injury/deployment
Methodological detailsfrequency-matched uninjured comparison group, self-reported questionnaires
  • Frequency-matched uninjured comparison group
  • Self-reported questionnaires

Main finding

Moderate or severe pain

Relative risk

1.1

95% CI 1.0–1.2

P < 0.001

Events by group

Injured vs Uninjured
RR 1.1 (95% CI 1.0–1.2); P < 0.001

As reported in the abstract

Overall frequency of moderate or severe pain
18% (n=202)

Observational data: associations, not effects.

Further findings

OutcomeAmputationNon-amputationRR (95% CI)P value
Moderate or severe pain, amputation vs non-amputation injury (subgroup)19%26%0.9 (0.9–1.0)P = 0.034

Mental health outcomes with at least moderate pain (after accounting for injury)

RR (95% CI)
At least moderate painPost-traumatic stress3.7 (2.7–5.0)
At least moderate painAnxiety3.2 (2.4–4.3)
At least moderate painDepression3.4 (2.7–4.5)

Original publication

Pain after combat injury in male UK military personnel deployed to Afghanistan. Br J Anaesth. Published 23 March 2024. doi:10.1016/j.bja.2024.02.019

Composed by AI from the published abstract and checked against it. How Briefs are made →

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