Pain severity during infiltration of local anesthesia before spinal anesthesia as a predictor of post-cesarean pain and Obstetric Quality-of-Recovery scores (ObsQoR-11): a prospective observational study
Authors' conclusion
Our findings suggest that pain during ILA may serve as a clinical predictor of post-cesarean pain; however, it was not associated with lower ObsQoR-11 scores.
Study context
- Population
- Patients undergoing cesarean delivery with neuraxial anesthesia; Infiltration of local anesthesia (ILA) with lidocaine 1% 3 mL before spinal anesthesia
- Participants
- 114 patients
- Exposure
- Mild vs moderate vs severe pain during ILA
- Mild ILAn = 83reference
- Moderate ILAn = 24
- Severe ILAn = 7
- Outcome
- Rest pain (NRS)
- Follow-up
- 24 hours postpartum
Main finding
As reported in the abstract
Mild ILA
20.0
Median · 95% CI 10.0–20.0
Moderate ILA
35
Median · 95% CI 20.0–50.0
Severe ILA
45.0
Median · 95% CI 30.0–60.0
P < 0.001
Observational data: associations, not effects.
Further findings
Median
| Outcome | Mild ILA | Moderate ILA | Severe ILA | P value |
|---|---|---|---|---|
| ObsQoR-11 score · 24 hours postpartum | 90.0 (95% CI 83.0–92.0) | 74.0 (95% CI 65.0–79.0) | 88.0 (95% CI 58.0–90.0) | P = 0.021 |
| Global health rating · 24 hoursAcross three groups; threshold P <0.013 for other outcomes | P = 0.010 |
- ObsQoR-11 score: not significantly different between groups (significance threshold P <0.017)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pain severity during infiltration of local anesthesia before spinal anesthesia as a predictor of post-cesarean pain and Obstetric Quality-of-Recovery scores (ObsQoR-11): a prospective observational study. Int J Obstet Anesth. Published 20 June 2025. doi:10.
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