Pediatric anesthesia & critical care

Patient and Process Outcomes among Pediatric Patients Undergoing Appendectomy during the COVID-19 Pandemic: An International Retrospective Cohort Study

AnesthesiologyPublished Retrospective cohort study

Main finding · Hospital LOSResult — go to the resultAdjusted coefficient 1 95% CI 0.39–1.61

Authors' conclusion

For children undergoing appendectomy, the COVID-19 pandemic did not significantly impact hospital length of stay.

Study context

Population
Patients younger than 18 yr undergoing primary appendectomy, 28 institutions of the PEACOC collaborative; matched on age, ASA Physical Status and sex
Participants
3,351 participants · 28 institutions
Exposure
COVID-19 pandemic period vs prepandemic period
  • Pandemicn = 1,618
  • Prepandemicn = 1,684reference
Outcome
Hospital LOS
Methodological detailsinternational, multicentre, matched cohorts
  • International
  • Multicentre
  • Matched cohorts

Main finding

As reported in the abstract

Adjusted coefficient

1

95% CI 0.39–1.61

P < 0.001

By group

Centres with significantly longer LOS in pandemic period
8
Centres with shorter LOS in pandemic period
13
Centres without significant difference
7

Observational data: associations, not effects.

Secondary outcomes

Complicated appendicitis

absolute difference 5.5%

OutcomeaOR (95% CI)P value
Complicated appendicitis1.32 (1.1–1.59)P = 0.003
OutcomeEstimateP value
Time to appendectomy, preoperative SARS-CoV-2 testing vs no testingadjusted coefficient 306 min (95% CI 241–371)P < 0.001
Hospital LOS, preoperative SARS-CoV-2 testing vs no testingadjusted coefficient 7.0 (95% CI 2.7–11.3)P = 0.002
  • Time to appendectomy, preoperative SARS-CoV-2 testing vs no testing: With testing 720 (IQR 430–1,112) min
  • Time to appendectomy, preoperative SARS-CoV-2 testing vs no testing: Without testing 414 (IQR 231–770) min
  • Hospital LOS, preoperative SARS-CoV-2 testing vs no testing: With testing 31 (IQR 20–83) h
  • Hospital LOS, preoperative SARS-CoV-2 testing vs no testing: Without testing 24 (IQR 14–68) h

Original publication

Patient and Process Outcomes among Pediatric Patients Undergoing Appendectomy during the COVID-19 Pandemic: An International Retrospective Cohort Study. Anesthesiology. Published 4 April 2023. doi:10.1097/aln.0000000000004570

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