Cardiac arrest & resuscitation
Pediatric out-of-hospital cardiac arrest outcomes by Child Opportunity Index, race and ethnicity
Authors' conclusion
Arrests occurring in lower COI areas and among Black/African American children are associated with lower odds of a favorable outcome. Lower bystander response partially explains these associations.
Study context
- Population
- Children ≤18 years with out-of-hospital cardiac arrest (OHCA), Cardiac Arrest Registry to Enhance Survival (CARES) registry
- Participants
- 17,903 children
- Exposure
- Child Opportunity Index quintiles and race and ethnicity
- Outcome
- Survival to hospital discharge with favorable neurological outcome (Pediatric Cerebral Performance Category ≤2)
Methodological detailsregistry-based (CARES), mediation analysis
- Registry-based (CARES)
- Mediation analysis
Main finding
As reported in the abstract
Adjusted odds ratio (95% CI)P value
Very low COI vs Very high COI
0.68(0.54–0.84)
P < 0.001Black/African American vs White
0.81(0.69–0.96)
P = 0.02- Favorable outcome, overall
- 1654/17,903 (9.2%)
Observational data: associations, not effects.
Further findings
Mediation by bystander response (adjusted percent mediated)
| Adjusted percent mediated (95% CI) | P value | |
|---|---|---|
| Lower COI quintilesPartial mediation | 11.7% (5.5–17.9) | P < 0.001 |
| Black/African AmericanPartial mediation | 15.6% (7.5–23.6) | P < 0.001 |
Arrest characteristics
- Arrests in lower Child Opportunity Index (COI) neighborhoods and in Black/African American children more often in infants, less often witnessed and less likely to receive bystander response
Original publication
Pediatric out-of-hospital cardiac arrest outcomes by Child Opportunity Index, race and ethnicity. Resuscitation. Published 16 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →