Perioperative medicine & outcomes
Perioperative Glucose Pragmatic (PROGRAM) Trial: Standardized Insulin Management in Surgical Patients
Authors' conclusion
Among surgical patients at high risk of intraoperative hyperglycemia, an automated insulin dosing reminder did not improve glycemic control or other outcomes compared with a glucose check reminder.
Study context
- Population
- Adults at high risk for intraoperative hyperglycemia undergoing major surgerycases in primary analysis
- Participants
- 4,558 adults
- Comparison
- Automated insulin dosing reminder vs glucose check reminder
- Interventionn = 1,947
- Routine caren = 2,611reference
- Outcome
- Hyperglycemia (glucose greater than 180 mg/dl) at the first postoperative measurement
- Follow-up
- 3 h or less postoperatively
Methodological detailssequential and repeated crossover design, single-centre (quaternary medical center), October 5, 2022 to October 26, 2023
- Sequential and repeated crossover design
- Single-centre (quaternary medical center)
- October 5, 2022 to October 26, 2023
Main finding
As reported in the abstract
Postoperative hyperglycemia (glucose >180 mg/dl) at first measurement ≤3 h postoperatively
Safety
Safety endpoints
- No difference between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Perioperative Glucose Pragmatic (PROGRAM) Trial: Standardized Insulin Management in Surgical Patients. Anesthesiology. Published 23 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →