Paediatric anaesthesia & critical care

Perioperative Outcomes and Transfusion Practices in Neonates Undergoing Sacrococcygeal Teratoma Resection: A Single Center Retrospective Case Series

Paediatr AnaesthPublished Retrospective case series

Authors' conclusion

Neonates undergoing SCT surgery had a high rate of blood transfusion (59%), replacing on average over a quarter of their blood volume, and a high composite adverse outcome rate (39%).

Study context

Population
Neonates undergoing sacrococcygeal teratoma (sacrococcygeal teratomas (SCT)) resection, Boston Children's Hospital, January 2012–April 2024
Participants
17 neonates
Exposure
Transfused vs not transfused
Outcome
Perioperative outcomes, including blood product transfusion practices
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Clinically significant postoperative event (composite) within 30 days

39%

Death within 30 days

1

Intraoperative blood transfusion

59%

Median RBC transfusion volume, mL/kg (0, 43)

24.8

Observational data: associations, not effects.

Further findings

Median tumor volume

Duration of anesthesia

Median

OutcomeTransfusedNot transfused
Tumor volume-to-weight ratio0.31 (IQR 0.10–0.77)0.02 (IQR 0.01–0.07)
  • Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup): Cystic median 28.1 (range 0–40) mL/kg
  • Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup): Non-cystic median 24.8 (range 0–60) mL/kg

Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup)

No statistically significant difference; more neonates with non-cystic tumors transfused (70% vs. 30%)

Original publication

Perioperative Outcomes and Transfusion Practices in Neonates Undergoing Sacrococcygeal Teratoma Resection: A Single Center Retrospective Case Series. Paediatr Anaesth. Published 10 March 2026. doi:10.1002/pan.70163

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