Paediatric anaesthesia & critical care
Perioperative Outcomes and Transfusion Practices in Neonates Undergoing Sacrococcygeal Teratoma Resection: A Single Center Retrospective Case Series
Authors' conclusion
Neonates undergoing SCT surgery had a high rate of blood transfusion (59%), replacing on average over a quarter of their blood volume, and a high composite adverse outcome rate (39%).
Study context
- Population
- Neonates undergoing sacrococcygeal teratoma (sacrococcygeal teratomas (SCT)) resection, Boston Children's Hospital, January 2012–April 2024
- Participants
- 17 neonates
- Exposure
- Transfused vs not transfused
- Outcome
- Perioperative outcomes, including blood product transfusion practices
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Clinically significant postoperative event (composite) within 30 days
39%
Death within 30 days
1
Intraoperative blood transfusion
59%
Median RBC transfusion volume, mL/kg (0, 43)
24.8
Observational data: associations, not effects.
Further findings
Median tumor volume
Duration of anesthesia
Median
| Outcome | Transfused | Not transfused |
|---|---|---|
| Tumor volume-to-weight ratio | 0.31 (IQR 0.10–0.77) | 0.02 (IQR 0.01–0.07) |
- Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup): Cystic median 28.1 (range 0–40) mL/kg
- Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup): Non-cystic median 24.8 (range 0–60) mL/kg
Intraoperative RBC volume transfused, cystic vs non-cystic tumors (subgroup)
- No statistically significant difference; more neonates with non-cystic tumors transfused (70% vs. 30%)
Original publication
Perioperative Outcomes and Transfusion Practices in Neonates Undergoing Sacrococcygeal Teratoma Resection: A Single Center Retrospective Case Series. Paediatr Anaesth. Published 10 March 2026. doi:10. 1002/ pan. 70163
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