Perioperative medicine & outcomes
Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature
Authors' conclusion
Literature analysis identified inconsistent methodology, leading to challenges in interpretation.
Study context
- Population
- Adults undergoing surgery, studies using a validated diagnostic scale for postoperative delirium169 studies
- Outcome
- Risk factors for postoperative delirium
Methodological detailsGRADE assessment
- GRADE assessment
Pooled result
As reported in the abstract
Risk factors for postoperative delirium (6 variables eligible for meta-analysis)
MD (95% CI)P value
Age
4.94(2.93–6.94)
P < 0.001Mini-Mental State Examination
−1.94(−3.6 to −0.27)
P = 0.0224Odds ratio (95% CI)P value
ASA physical status >2
2.27(1.47–3.52)
P < 0.001Charlson Comorbidity Index ≥2
1.9(1.11–3.25)
P = 0.0202Original publication
Perioperative risk factors associated with increased incidence of postoperative delirium: systematic review, meta-analysis, and Grading of Recommendations Assessment, Development, and Evaluation system report of clinical literature. Br J Anaesth. Published 7 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →