Obstetric anesthesia

Persistent opioid use after cesarean delivery in the United States of America: a systematic review

Int J Obstet AnesthPublished Systematic review

Study context

Population
Opioid-naïve individuals undergoing cesarean delivery in the US, 2001–2016 (insurance claims data)
Participants
486,263 individuals · 4 retrospective studies
Outcome
Incidence of persistent opioid use after cesarean delivery (generally ≥2 opioid prescriptions filled within the first year)
Methodological detailsqualitative analysis
  • Qualitative analysis

Pooled result

As reported in the abstract

Rate of persistent opioid use after cesarean delivery · up to 12 months postpartum

Range of rates across studies

0.12% to 2.2%

Highest rate in private insurance claims 2008–2016

2.2%

Individuals at risk

from 1:1000 to 1:50

Further pooled results

Projected number continuing opioids past the fourth trimester (of 1.2 million US cesarean deliveries annually)

As few as
1440
As many as
26 400

Original publication

Persistent opioid use after cesarean delivery in the United States of America: a systematic review. Int J Obstet Anesth. Published 27 February 2023. doi:10.1016/j.ijoa.2023.103644

Composed by AI from the published abstract and checked against it. How Briefs are made →

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