Perioperative medicine & outcomes
Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study
Authors' conclusion
Compared with those without hyperlipidemia, patients with hyperlipidemia had higher POD incidence. Elevated serum TC and TG levels are independent risk factors for POD in patients with hyperlipidemia.
Study context
- Population
- Adults scheduled for colorectal cancer surgery in 2023
- Participants
- 555 adults
- Exposure
- Hyperlipidemia vs non-hyperlipidemia
- Outcome
- POD incidence
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mortality and cognitive decline in patients with hyperlipidemia, with vs without postoperative delirium (POD) (subgroup) · 1 year
- Significantly higher rates of mortality and cognitive decline with POD than without POD
- P < 0.001
Independent risk factors for POD in patients with hyperlipidemia (multifactorial logistic prediction model)
- Seven independent risk factors: education, preoperative total cholesterol (TC), preoperative triglyceride (TG), diet, history of hypertension, Sedation-Agitation Scale, postoperative trimethylamine N-oxide level; model had highest predictive value
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study. J Clin Anesth. Published 2 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →