Pre-hospital ECPR for refractory cardiac arrest – The PRECARE pilot feasibility study
Authors' conclusion
Pre-hospital ECPR delivery by trained pre-hospital medical teams is possible and reduces OHCA low flow times.
Study context
- Population
- Patients <70 years with witnessed refractory of hospital cardiac arrest (OHCA), initial shockable rhythm, within 45-minute radius of the mobile team123 cardiac arrests attended
- Participants
- 12 patients
- Outcome
- Feasibility of pre-hospital ECPR delivered by pre-hospital physicians
Methodological detailsopen-label, pilot, August 2023 to June 2024, over 103 recruitment days
- Open-label
- Pilot
- August 2023 to June 2024, over 103 recruitment days
Main finding
As reported in the abstract
Feasibility
Pre-hospital ECPR
10%
12
- Patients receiving pre-hospital ECPR among attended cardiac arrests
- 12 (10%)
- Cases per shifts
- one case per 8 shifts
Further findings
Time from dispatch to team arrival
- Mean time from dispatch to team arrival
- 18.5 min (range 9-29)
Time from decision to ECMO flow
- Mean time from decision to ECMO flow
- 17 min (range 10-34)
Total low flow time (arrest to ECMO flow)
- Mean total low flow time (arrest to ECMO flow)
- 39 min (range 24-56)
Liberation from VA ECMO support
- Patients successfully liberated from VA ECMO support
- 4 (33%)
Survival to hospital discharge neurologically intact (CPC 1-2)
- Patients survived to hospital discharge neurologically intact (CPC 1-2)
- 3 (25%)
Original publication
Pre-hospital ECPR for refractory cardiac arrest – The PRECARE pilot feasibility study. Resuscitation. Published 12 May 2025. doi:10.
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