Pediatric anesthesia & critical care

Predicting obstructive sleep apnoea and perioperative respiratory adverse events in children: role of upper airway collapsibility measurements

Br J AnaesthPublished Diagnostic accuracy study

Performance · Moderate-to-severe OSAResult — go to the resultOdds ratio 1.71 95% CI 1.2–2.8

Authors' conclusion

Measurement of PCLOSE after induction of anaesthesia can reliably identify moderate or severe OSA but not perioperative respiratory adverse events in children before adenotonsillectomy.

Study context

Population
Children scheduled for elective adenotonsillectomy, in-laboratory polysomnography 2–12 weeks before surgery
Participants
52 children
Comparison
PCLOSE under anaesthesia for predicting obstructive sleep apnoea (OSA) and perioperative respiratory adverse events
  • PCLOSEn = 52
Outcome
Prediction of moderate-to-severe OSA and perioperative respiratory adverse events by PCLOSE
Methodological detailsprospective, polysomnography reference standard
  • Prospective
  • Polysomnography reference standard

Performance

Moderate-to-severe OSA

Odds ratio

1.71

95% CI 1.2–2.8

P = 0.011

By group

PCLOSE

Sensitivity (threshold −4.0 cm H2O)
100%
Specificity
64.7%
AUC
0.857

PCLOSE

Sensitivity (threshold −4.0 cm H2O)100%
Specificity64.7%
AUC0.857
PCLOSE
OR 1.71 (95% CI 1.2–2.8); P = 0.011

As reported in the abstract

Further findings

Perioperative respiratory adverse events

OR (95% CI)P value
PCLOSE1.0 (0.8–1.1)P = 0.641

Airway collapse during PCLOSE and OSA status

Airway collapse observed
42 (81%)
Collapse: no OSA
19 of 42 (45%)
Collapse: mild OSA
15 (36%)
Collapse: moderate-to-severe OSA
eight (19%)
No collapse: all without OSA
10

Original publication

Predicting obstructive sleep apnoea and perioperative respiratory adverse events in children: role of upper airway collapsibility measurements. Br J Anaesth. Published 25 October 2023. doi:10.1016/j.bja.2023.09.021

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