Pediatric anesthesia & critical care
Predicting obstructive sleep apnoea and perioperative respiratory adverse events in children: role of upper airway collapsibility measurements
Performance · Moderate-to-severe OSAResult — go to the resultOdds ratio 1.71 95% CI 1.2–2.8Authors' conclusion
Measurement of PCLOSE after induction of anaesthesia can reliably identify moderate or severe OSA but not perioperative respiratory adverse events in children before adenotonsillectomy.
Study context
- Population
- Children scheduled for elective adenotonsillectomy, in-laboratory polysomnography 2–12 weeks before surgery
- Participants
- 52 children
- Comparison
- PCLOSE under anaesthesia for predicting obstructive sleep apnoea (OSA) and perioperative respiratory adverse events
- PCLOSEn = 52
- Outcome
- Prediction of moderate-to-severe OSA and perioperative respiratory adverse events by PCLOSE
Methodological detailsprospective, polysomnography reference standard
- Prospective
- Polysomnography reference standard
Performance
Moderate-to-severe OSA
Odds ratio
1.71
95% CI 1.2–2.8
P = 0.011
By group
PCLOSE
- Sensitivity (threshold −4.0 cm H2O)
- 100%
- Specificity
- 64.7%
- AUC
- 0.857
PCLOSE
Sensitivity (threshold −4.0 cm H2O)100%
Specificity64.7%
AUC0.857
PCLOSE
OR 1.71 (95% CI 1.2–2.8); P = 0.011
As reported in the abstract
Further findings
Perioperative respiratory adverse events
| OR (95% CI) | P value | ||
|---|---|---|---|
| PCLOSE | 1.0 (0.8–1.1) | P = 0.641 | |
| 0.512Odds ratio (log scale) |
Airway collapse during PCLOSE and OSA status
- Airway collapse observed
- 42 (81%)
- Collapse: no OSA
- 19 of 42 (45%)
- Collapse: mild OSA
- 15 (36%)
- Collapse: moderate-to-severe OSA
- eight (19%)
- No collapse: all without OSA
- 10
Original publication
Predicting obstructive sleep apnoea and perioperative respiratory adverse events in children: role of upper airway collapsibility measurements. Br J Anaesth. Published 25 October 2023. doi:10. 1016/ j. bja. 2023. 09. 021
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