Perioperative medicine & outcomes

Preoperative electrocardiography for predicting cardiovascular events after noncardiac surgery: a secondary analysis of two prospective cohorts

Br J AnaesthPublished Secondary analysis of two prospective cohorts

Authors' conclusion

Preoperative ECG findings, assessed by including conventional waveform features and the PreOpNet algorithm, provide limited incremental predictive value for cardiovascular risk assessment before noncardiac surgery.

Study context

Population
Patients undergoing major noncardiac surgery in China, 2019–2023
Participants
6,080 patients
Comparison
Clinical risk scores with vs without preoperative ECG findings
Primary endpoint
Composite of any cardiovascular events
Follow-up
30 days after surgery
Methodological detailsprognostic model comparison, nested logistic regression models
  • Prognostic model comparison
  • Nested logistic regression models

Primary result

As reported in the abstract

Discrimination for any cardiovascular events (ΔAUC vs clinical risk score)

ΔAUC

Conventional ECG features vs Clinical risk score · added to Revised Cardiac Risk Index
0.035
PreOpNet vs Clinical risk score · added to Revised Cardiac Risk Index
0.032
Conventional ECG features vs Clinical risk score · added to Gupta risk score
0.010
PreOpNet vs Clinical risk score · added to Gupta risk score
0.006
Postoperative cardiovascular events
733 (12.1%)

Secondary outcomes

Patients with MACE
174 (2.9%)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Preoperative electrocardiography for predicting cardiovascular events after noncardiac surgery: a secondary analysis of two prospective cohorts. Br J Anaesth. Published 31 July 2026. doi:10.1016/j.bja.2026.06.025

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