Preoperative pain sensitivity and its correlation with postoperative acute and chronic pain: a systematic review and meta-analysis
Authors' conclusion
Lower PPT and EPT, and higher TSP are associated with acute postoperative pain while only TSP is associated with chronic postoperative pain.
Study context
- Population
- Surgical patients with preoperative pain sensitivity assessment70 studies
- Outcome
- Correlation between preoperative pain sensitivity and postoperative pain
Methodological detailsrandom-effects model, subgroup analyses, multilevel (three-level) meta-analysis
- Random-effects model
- Subgroup analyses
- Multilevel (three-level) meta-analysis
Pooled result
As reported in the abstract
Correlation of preoperative pain sensitivity (PPS) measures with postoperative pain
Pressure pain threshold (PPT), r
−0.15
95% CI −0.23 to −0.07
Electrical pain threshold (EPT), r
−0.28
95% CI −0.42 to −0.14
Temporal summation of pain (TSP), r
0.21
95% CI 0.12–0.30
Pain Sensitivity Questionnaire (PSQ), r
0.25
95% CI 0.13–0.37
Further pooled results
Acute vs chronic postoperative pain (subgroup)
- Only TSP associated with both acute and chronic postoperative pain; PPT, EPT and PSQ associated with acute pain only
PSQ in multilevel (three-level) meta-analysis
- PSQ not associated with postoperative pain
Original publication
Preoperative pain sensitivity and its correlation with postoperative acute and chronic pain: a systematic review and meta-analysis. Br J Anaesth. Published 15 June 2024. doi:10.
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