Perioperative medicine & outcomes
Preoperative survey to evaluate the patients' allergy list and its relevance to perioperative care
Authors' conclusion
A significant portion of the documented allergies in children are not true allergies, but rather recognized adverse effects (apnea from an opioid, renal failure from an NSAIDs) or other nonallergic concerns (gastrointestinal upset such as nausea).
Study context
- Population
- Patients ≤ 21 years presenting for surgery in the main operating room with a drug allergy listed on the EMRmedications surveyed
- Participants
- 301 patients
- Exposure
- True allergy vs Unlikely true allergy vs Not an allergy
- True allergyn = 135
- Unlikely true allergyn = 73
- Not an allergyn = 93
- Outcome
- Origin, authenticity and impact on perioperative care of allergies listed in the EMR
Methodological detailspreoperative survey, physician review
- Preoperative survey
- Physician review
Main finding
As reported in the abstract
Validity of listed drug allergies after physician review (301 surveyed medications)
Observational data: associations, not effects.
Further findings
Care alterations during surgery · uncommon regardless of assessment
Patients with more than one drug allergy listed
- Patients with >1 listed drug allergy
- 70 (28%)
Listed allergy classes (of 351)
- Penicillin family
- 155 (44%)
- Cephalosporins
- 26 (7%)
- Sulfonamides
- 16 (5%)
- Other antimicrobial agents
- 36 (10%)
- NSAIDs
- 27 (8%)
- Opioids
- 15 (4%)
- Miscellaneous other medications
- 76 (22%)
Original publication
Preoperative survey to evaluate the patients' allergy list and its relevance to perioperative care. Paediatr Anaesth. Published 12 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →