ICU sedation, delirium & recovery
Prognosis of critically ill patients with extreme acidosis: A retrospective study
Authors' conclusion
Among critically ill patients with extreme acidosis, the primary disorder is not associated with mortality, but it is associated with the use of vasopressors and MV, the duration of MV, and the length of ICU and hospital stay.
Study context
- Population
- Critically ill patients admitted to the intensive care unit (ICU) with pH <7231 admitted with pH < 7
- Participants
- 222 patients
- Exposure
- Respiratory vs metabolic vs mixed extreme acidosis
- Respiratory acidosisn = 25
- Metabolic acidosisn = 75
- Mixed acidosisn = 122
- Outcome
- In-hospital mortality
Methodological detailsSimplified Stewart approach used to analyse causes of acidosis
- Simplified Stewart approach used to analyse causes of acidosis
Main finding
As reported in the abstract
P = 0.26
- Overall mortality
- 42.8%
Observational data: associations, not effects.
Secondary outcomes
Mortality by lactate, unmeasured-anion acidosis (subgroup)
P = 0.007
Vasopressor and mechanical ventilation (MV) use, MV duration, ICU and hospital LOS
- Primary disorder affected vasopressor and MV use, MV duration and ICU and hospital LOS
Original publication
Prognosis of critically ill patients with extreme acidosis: A retrospective study. J Crit Care. Published 20 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →