Cardiac arrest & resuscitation
Prognostic impact of bystander-patient relationship and age in patients with out-of-hospital cardiac arrest
Authors' conclusion
Patients with OHCA witnessed by family members had worse neurological outcomes than those witnessed by friends, colleagues, and passersby. This association differed by patient age, with family-member-witnessed OHCA associated with more favorable outcomes in younger patients but poorer outcomes in the elderly.
Study context
- Population
- Adults with witnessed out-of-hospital cardiac arrest (OHCA), All-Japan Utstein Registry, 2005–2023; age categories 18–69, 70–79, 80–89, ≥90 years
- Participants
- 554,923 adults
- Exposure
- Family members vs Friends and colleagues vs Passersby
- Family membersn = 459,841
- Friends and colleaguesn = 55,112
- Passersbyn = 39,970
- Outcome
- Neurologically favorable survival
- Follow-up
- 1 month
Methodological detailsnationwide registry, multivariable analysis
- Nationwide registry
- Multivariable analysis
Main finding
As reported in the abstract
- Difference across the 3 groups
- P < 0.001
Observational data: associations, not effects.
Further findings
Neurological outcomes, younger patients aged 20-40 years (subgroup)
- OHCA witnessed by family members related to better neurological outcomes
Proportion witnessed by family members with advancing age
- Increased with advancing age
- P < 0.001
Original publication
Prognostic impact of bystander-patient relationship and age in patients with out-of-hospital cardiac arrest. Resuscitation. Published 25 September 2026. doi:10.
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