PROSPECT methodology for developing procedure‐specific pain management recommendations: an update

Included RCTs must be prospectively registered on a publicly accessible trials database; study design, incl. primary outcome, in the registration should coincide with the published manuscript

Placebo-controlled studies of paracetamol, NSAIDs, cyclo-oxygenase-2-specific inhibitors or opioids alone will not be included

Studies comparing one drug with another of the same class will not be included

Cochrane Collaboration risk of bias tool for quality of reporting of methodology and results

Modified Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach for grading level of evidence and strength of recommendations