Perioperative medicine & outcomes

Prospective comparison of three methods for detecting peri‐operative neurocognitive disorders in older adults undergoing cardiac and non‐cardiac surgery

AnaesthesiaPublished Prospective observational study

An erratum to this article was published (Anaesthesia, Sep 2024 ↗)

Authors' conclusion

There seems to be little to no pre-operative, postoperative or pre- to postoperative correlation between these tests and the neuropsychological assessment in older adults without pre-operative cognitive impairment.

Study context

Population
Elective surgical patients aged ≥ 65 years (cardiac and non-cardiac surgery), recruited September 2019–January 202128 (27%) lost to follow-up
Participants
105 patients
Exposure
Modified Telephone Interview for Cognitive Status and Montreal Cognitive Assessment vs neuropsychological assessment
Outcome
Correlation of tests with cognitive domain scores
Methodological detailssingle-centre, Tests repeated at approximately four to eight postoperative weeks
  • Single-centre
  • Tests repeated at approximately four to eight postoperative weeks

Main finding

As reported in the abstract

Pre-operative Modified Telephone Interview for Cognitive Status vs cognitive domain scores: very weakly to moderately correlated

r = 0.09-0.41

Pre-operative Montreal Cognitive Assessment vs cognitive domain scores: very weakly to weakly correlated

r = 0.17-0.37

Postoperative Modified Telephone Interview for Cognitive Status vs cognitive domain scores: very weakly to weakly correlated

r = 0.09-0.36

Postoperative Montreal Cognitive Assessment vs cognitive domain scores: very weakly to weakly correlated

r = 0.07-0.36

Observational data: associations, not effects.

Original publication

Prospective comparison of three methods for detecting peri‐operative neurocognitive disorders in older adults undergoing cardiac and non‐cardiac surgery. Anaesthesia. Published 11 January 2023. doi:10.1111/anae.15965

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