Pediatric anesthesia & critical care

Prospective development and validation of a universal classification for paediatric videolaryngoscopic tracheal intubation: the PeDiAC score

AnaesthesiaPublished Prospective observational study

Authors' conclusion

We developed and validated a specifically tailored classification for paediatric videolaryngoscopic tracheal intubation with excellent diagnostic performance and calibration that outperformed the Cormack and Lehane classification.

Study context

Population
Children undergoing tracheal intubation with C-MAC videolaryngoscopes for elective surgical procedures
Participants
809 children · 904 intubation episodes
Exposure
PeDiAC score vs Cormack and Lehane classification
Outcome
Diagnostic performance (AUC) of the PeDiAC score for classifying difficult videolaryngoscopic tracheal intubation vs Cormack and Lehane
Methodological detailsdiagnostic model development and validation, multivariable logistic regression, external validation of VIDIAC score, Conducted within a structured universal videolaryngoscopy implementation programme, Eight factors selected by 100-times repeated 10-fold cross-validated LASSO regression
  • Diagnostic model development and validation
  • Multivariable logistic regression
  • External validation of VIDIAC score
  • Conducted within a structured universal videolaryngoscopy implementation programme
  • Eight factors selected by 100-times repeated 10-fold cross-validated LASSO regression

Main finding

As reported in the abstract

AUC for difficult videolaryngoscopic intubation
GroupAUC
PeDiAC score0.97 (95%CI 0.96-0.99)
Cormack and Lehane0.69 (95%CI 0.62-0.76)

AUC

PeDiAC score0.97 (95%CI 0.96-0.99)
Cormack and Lehane0.69 (95%CI 0.62-0.76)
  • PeDiAC score vs Cormack and Lehane: P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeVIDIAC scoreCormack and LehaneP value
External validation of VIDIAC score: AUCVIDIAC score vs Cormack and LehaneP = 0.018
AUC0.80 (95%CI 0.73-0.87)0.69 (95%CI 0.62-0.76)

Original publication

Prospective development and validation of a universal classification for paediatric videolaryngoscopic tracheal intubation: the PeDiAC score. Anaesthesia. Published 7 August 2024. doi:10.1111/anae.16394

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