ICU sedation, delirium & recovery
Proteomics for the Discovery of Clinical Delirium Biomarkers: A Systematic Review of Major Studies
Authors' conclusion
By reviewing the distribution of protein biomarker candidates from these studies, we conclude that a panel of proteins, rather than a single biomarker, would allow for discriminating delirium cases from noncases.
Study context
- Population
- Human geriatric subjects in untargeted proteomic discovery studies of delirium biomarkers, 2016–20218 studies
- Outcome
- Perioperative delirium biomarkers identified
Methodological detailsuntargeted proteomic discovery studies, two independent reviewers, Searched MEDLINE, Cochrane Central, Web of Science, SCOPUS and Dimensions, 2016–2021
- Untargeted proteomic discovery studies
- Two independent reviewers
- Searched MEDLINE, Cochrane Central, Web of Science, SCOPUS and Dimensions, 2016–2021
Pooled result
As reported in the abstract
- Unique perioperative biomarkers identified
- 370
Original publication
Proteomics for the Discovery of Clinical Delirium Biomarkers: A Systematic Review of Major Studies. Anesth Analg. Published 29 December 2022. doi:10.
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