Perioperative medicine & outcomes
Psoas muscle mass index as a predictor of long-term mortality and severity of complications after major intra-abdominal colorectal surgery – A retrospective analysis
Main finding · 2-year mortalityResult — go to the resultAdjusted odds ratio 1.79 95% CI 1.03–3.10Authors' conclusion
Sarcopenia defined by psoas muscle mass is an independent predictor of 2-year mortality, major complications and severity of complications after major colorectal surgery
Study context
- Population
- Patients attending preoperative assessment clinic before major elective colorectal surgery with abdominal CT up to 120 days before surgery, York Hospital, 2015–2020
- Participants
- 639 patients
- Exposure
- Sarcopenic vs non-sarcopenic patients
- Outcome
- 2-year mortality
- Follow-up
- 2 years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Adjusted odds ratio
1.79
95% CI 1.03–3.10
P = 0.037
Sarcopenic vs Non-sarcopenic
aOR 1.79 (95% CI 1.03–3.10); P = 0.037
- Survival at 2 years significantly reduced in sarcopenic patients (log-rank test)
- P = 0.012
Observational data: associations, not effects.
Secondary outcomes
Major complications (Clavien-Dindo)
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Sarcopenia | 1.69 (1.04–2.74) | P = 0.034 | |
| 0.20.5125Adjusted odds ratio (log scale) |
- Major complications (Clavien-Dindo): only statistically significant predictor in multivariable logistic regression
Comprehensive complication index (CCI) score in patients with complications
- Sarcopenia associated with estimated increase in CCI score (multivariable linear regression)
- 16.6%
2-year survival
- Significantly reduced in sarcopenic patients (log-rank test)
- P = 0.012
LOS
- Sarcopenia not associated with length of stay
Original publication
Psoas muscle mass index as a predictor of long-term mortality and severity of complications after major intra-abdominal colorectal surgery – A retrospective analysis. J Clin Anesth. Published 10 November 2022. doi:10.
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