Cardiac arrest & resuscitation
Quantitative EEG reactivity induced by electrical stimulation predicts good outcome in comatose patients after cardiac arrest
Authors' conclusion
EEG reactivity induced by the standardized electrical stimulation in combination with quantitative analysis is a promising formula for post-CA comatose patients, with increased predictive accuracy.
Study context
- Population
- Comatose patients after cardiac arrest (CA), Xuanwu Hospital, Beijing, China, 2016–202352 analysed
- Participants
- 58 patients
- Exposure
- EEG reactivity to standardized electrical vs traditional pain stimulation, by visual and quantitative analysis
- Outcome
- Prediction of good neurological outcome (CPC 1-2 vs poor CPC 3-5)
- Follow-up
- Within 6 months
Methodological detailssingle-centre, randomly assigned stimulation type
- Single-centre
- Randomly assigned stimulation type
Main finding
As reported in the abstract
Good outcome prediction (AUC)
| Group | AUC |
|---|---|
| Electrical, quantitative | 0.932 |
| Electrical, visual | 0.838 |
| Pain, quantitative | 0.849 |
| Pain, visual | 0.770 |
AUC
Electrical, quantitative0.932
Electrical, visual0.838
Pain, quantitative0.849
Pain, visual0.770
- Electrical, quantitative vs Pain, quantitative: P = 0.048
- Electrical, quantitative vs Electrical, visual: P = 0.039
- Electrical, quantitative vs Pain, visual: P = 0.004
Observational data: associations, not effects.
Further findings
Good outcome (CPC 1-2) · within 6 months
- Patients with good outcomes
- 19 (36.5%)
Original publication
Quantitative EEG reactivity induced by electrical stimulation predicts good outcome in comatose patients after cardiac arrest. Ann Intensive Care. Published 27 June 2024. doi:10.
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