Perioperative medicine & outcomes
Racial and Ethnic Disparities in Failure-to-Rescue After Postoperative Sepsis After Noncardiac Surgery
Authors' conclusion
Black and Hispanic individuals experienced higher rates of postoperative sepsis but did not experience higher rates of failure-to-rescue.
Study context
- Population
- Patients undergoing inpatient noncardiac surgery, American College of Surgeons NSQIP, 2018–2021
- Exposure
- Black, Hispanic and Asian vs White individuals
- Outcome
- Failure-to-rescue (30-day mortality among patients who developed postoperative sepsis or septic shock)
- Follow-up
- 30-day
Methodological detailsmultivariable logistic regression, registry (ACS NSQIP)
- Multivariable logistic regression
- Registry (ACS NSQIP)
Main finding
As reported in the abstract
Failure-to-rescue after sepsis and after septic shock
Adjusted odds ratio (95% CI)P value
Black vs WhiteFTR after sepsis
0.71(0.54–0.94)
P = 0.017Black vs WhiteFTR after septic shock
0.93(0.80–1.08)
P = 0.35Hispanic vs WhiteFTR after septic shock
0.87(0.72–1.06)
P = 0.16Asian vs WhiteFTR after septic shock
1.06(0.8–1.37)
P = 0.67Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| Development of postoperative sepsisBlack vs White | 1.29 (1.23–1.35) | P < 0.001 | |
| Development of postoperative sepsisHispanic vs White | 1.15 (1.09–1.21) | P < 0.001 | |
| Development of postoperative septic shockBlack vs White | 1.28 (1.21–1.36) | P < 0.001 | |
| Development of postoperative septic shockAsian vs White | 0.84 (0.75–0.93) | P = 0.002 | |
| 0.512Adjusted odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Racial and Ethnic Disparities in Failure-to-Rescue After Postoperative Sepsis After Noncardiac Surgery. Anesth Analg. Published 16 June 2025. doi:10.
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