Pediatric anesthesia & critical care
Racial and Ethnic Disparity in Approach for Pediatric Intensive Care Unit Research Participation
Authors' conclusion
In this cohort study of consent rates for PICU research, multiple sociodemographic factors were associated with lower rates of consent, partly attributable to disparate rates of approach.
Study context
- Population
- Children eligible for pediatric intensive care unit (PICU) studies requiring prospective consent, Children's Hospital of Philadelphia, July 2011–December 2021
- Participants
- 3,154 children
- Exposure
- Race and ethnicity, language, religion and Social Deprivation Index (SDI) vs approach and consent rates for PICU research
- Outcome
- Rates of approach among eligible patients, consent among eligible patients, and consent among those approached
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Consent among children approached (Black vs White)
Black vs WhiteEstimate (95% CI)
Unadjusted
OR 0.73(0.55–0.97)
Adjusted
aOR 0.68(0.49–0.93)
Observational data: associations, not effects.
Further findings
Proportion of reduced consent odds in Black individuals mediated by lower probability of approach (mediation analysis)
- Mediated proportion
- 51.0% (95% CI 11.8%-90.2%)
Original publication
Racial and Ethnic Disparity in Approach for Pediatric Intensive Care Unit Research Participation. JAMA Netw Open. Published 1 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →