Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial
Primary result · Postoperative pain score (NRS)Result — go to the resultBootstrap corrected actual difference 1.5 95% CI 0.4–2.6Authors' conclusion
Postoperative pain scores were significantly improved in nociception level index-guided patients.
Study context
- Population
- ASA 1–3 adults undergoing major abdominal surgery under sevoflurane/fentanyl anesthesiacompleted the study
- Participants
- 75 participants
- Comparison
- NOL-guided fentanyl dosing vs standard care
- NOLn = 36
- SOCn = 39reference
- Primary endpoint
- Postoperative pain scores (Numerical Rating Scale (NRS) 0-10)
- Follow-up
- 90 min
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
Postoperative pain score (NRS)
Bootstrap corrected actual difference
1.5
95% CI 0.4–2.6
By group
NOL
3.0
median · IQR 0.0–5.0
SOC
5.0
median · IQR 3.0–6.0
SOC vs NOL
Bootstrap corrected actual difference 1.5 (95% CI 0.4–2.6)
As reported in the abstract
Further findings
Postoperative morphine consumption and intraoperative fentanyl consumption
- No difference
Original publication
Reduced postoperative pain in patients receiving nociception monitor guided analgesia during elective major abdominal surgery: a randomized, controlled trial. J Clin Monit Comput. Published 17 August 2022. doi:10.
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