Perioperative medicine & outcomes
Regional versus general anesthesia for total hip and knee arthroplasty: a nationwide retrospective cohort study
Main finding · 30-day mortalityResult — go to the resultOdds ratio 0.69 95% CI 0.60–0.80Authors' conclusion
RA compared with GA was associated with improved 30-day and 90-day survival outcomes in patients who underwent TJA. However, the postoperative complication rate did not differ significantly.
Study context
- Population
- Adults undergoing total knee or hip arthroplasty, National Health Insurance Service of South Korea, 2016–2021186,590 propensity score (PS)-matched analysed
- Participants
- 517,960 adults
- Exposure
- Regional anesthesia (RA) vs general anesthesia (GA) for total knee or hip arthroplasty
- RAn = 380,698
- GAn = 137,262reference
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailspopulation-based, nationwide, propensity-score matched
- Population-based
- Nationwide
- Propensity-score matched
Main finding
As reported in the abstract
Odds ratio
0.69
95% CI 0.60–0.80
P < 0.001
RA vs GA
OR 0.69 (95% CI 0.60–0.80); P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| 90-day mortality · 22% lower · PS-matched cohort | 0.78 (0.72–0.85) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
Safety
| Outcome | P value |
|---|---|
| Total postoperative complications | P = 0.105 |
Total postoperative complications
- Did not differ significantly between the two groups
Original publication
Regional versus general anesthesia for total hip and knee arthroplasty: a nationwide retrospective cohort study. Reg Anesth Pain Med. Published 30 April 2024. doi:10.
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