Neuroanesthesia & neurocritical care
Relationship between intraoperative hypertension and postoperative ischemic stroke in neurosurgery—a retrospective cohort study
Authors' conclusion
Intraoperative hypertension is a significant predictor of postoperative ischemic stroke in neurosurgical patients, with peak value, the duration, and AUC all demonstrating independent predictive values.
Study context
- Population
- Patients with brain tumors undergoing craniotomies, Chongqing University Cancer Hospital, January 2017–December 2023included in final analysis
- Participants
- 1,786 patients
- Exposure
- Intraoperative hypertension indices: peak mean arterial pressure (MAP), duration, AUC
- Outcome
- Postoperative in-hospital acute ischemic stroke
Methodological detailssingle-centre, multivariate logistic regression, restricted cubic spline analysis, quartile analysis
- Single-centre
- Multivariate logistic regression
- Restricted cubic spline analysis
- Quartile analysis
Main finding
As reported in the abstract
Postoperative in-hospital acute ischemic stroke by intraoperative hypertension thresholds (quartile analysis)
Adjusted odds ratio (95% CI)
Peak value > 123 mmHg
2.118(1.360–3.297)
Duration > 5 min
1.604(1.033–2.491)
AUC > 530 mmHg*min
1.811(1.165–2.816)
Observational data: associations, not effects.
Original publication
Relationship between intraoperative hypertension and postoperative ischemic stroke in neurosurgery—a retrospective cohort study. Perioper Med (Lond). Published 27 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →