Risk Factors and Prediction of Chronic Postsurgical Pain Among Patients With Distal Lower Extremity Fracture: Cohort Analysis
Authors' conclusion
This study demonstrates that pain management strategies, surgical approaches, and patient psychological factors collectively influence the development of CPSP.
Study context
- Population
- Patients with distal lower extremity fracture undergoing surgical repairfinal cohort
- Participants
- 818 patients
- Outcome
- Chronic postsurgical pain (CPSP)
Methodological details1-year follow-up, Least Absolute Shrinkage and Selection Operator (LASSO) regression, information gain analysis and multivariable logistic regression, web-based risk calculator
- 1-year follow-up
- LASSO regression, information gain analysis and multivariable logistic regression
- Web-based risk calculator
Performance
As reported in the abstract
CPSP incidence and prediction model performance
- Chronic postsurgical pain (CPSP) incidence
- 38.4%
- Neuropathic pain among patients with CPSP
- 18.2%
- Optimism-corrected AUC, development cohort
- 0.872
- Optimism-corrected AUC, validation cohort
- 0.838
- Independent variables associated with CPSP: postoperative analgesic technique, fixation type, preoperative clinical management, numerical rating scale (NRS) score on day of visit and POD 1
- 6
Original publication
Risk Factors and Prediction of Chronic Postsurgical Pain Among Patients With Distal Lower Extremity Fracture: Cohort Analysis. Anesth Analg. Published 14 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →