Cardiac arrest & resuscitation

Risk factors for failure of the first intubation attempt during cardiopulmonary resuscitation in out-of-hospital emergency settings: What about chest compression?

ResuscitationPublished Secondary analysis of a prospective observational multicentre study

Authors' conclusion

The first intubation attempt failed in 34% of cases, and ongoing chest compressions during intubation was one of six variables associated with the risk of failure.

Study context

Population
OHCA patients undergoing tracheal intubation (TI) during resuscitation in out-of-hospital emergency settingsanalysed
Participants
848 patients
Comparison
Risk factors for failure of the first TI attempt during CPR, incl. ongoing chest compression
Primary endpoint
Failure of the first intubation attempt

Primary result

As reported in the abstract

Failure of the first TI attempt
Odds ratio (95% CI)
Operator with ≤ 50 prior intubations
2.0(1.4–2.9)
Male patient gender
1.5(1.0–2.3)
Small inter-incisor space
3.4(2.2–5.4)
Ear, nose, and throat disease
2.8(1.8–4.4)
Vomiting
2.1(1.4–3.2)
Continued chest compression during TI attempt
1.6(1.1–2.3)
First TI attempts failed
291 (34.3%)

Original publication

Risk factors for failure of the first intubation attempt during cardiopulmonary resuscitation in out-of-hospital emergency settings: What about chest compression? Resuscitation. Published 26 April 2025. doi:10.1016/j.resuscitation.2025.110623

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