Risk-standardizing hospital rates of survival for pediatric in-hospital cardiopulmonary resuscitation (CPR) events
Authors' conclusion
We developed and validated a model to risk-standardize hospital rates of survival for children undergoing CPR, including those with bradycardia and poor perfusion.
Study context
- Population
- Children who underwent in-hospital CPR, Get With the Guidelines-Resuscitation registry, 2016–2023
- Participants
- 8,080 children
- Outcome
- Survival to hospital discharge (model to calculate hospital risk-standardized survival rates, risk-standardized survival rates (RSSRs))
Methodological detailsmulticentre registry, hierarchical logistic regression, derivation and validation cohorts
- Multicentre registry
- Hierarchical logistic regression
- Derivation and validation cohorts
Main finding
As reported in the abstract
Model performance and hospital RSSRs
- Full model, 16 predictors, derivation cohort: c-statistic
- 0.772
- Parsimonious model, 13 predictors: c-statistic
- 0.769
- Calibration in validation cohort: R2
- 0.993
- Median RSSR among 100 hospitals with ≥5 CPR events (IQR 50.1-54.5%; range 40.5-62.9%)
- 51.8%
- Adjusted median OR between hospitals
- 1.32 (95% CI 1.18-1.43)
Observational data: associations, not effects.
Further findings
Bradycardia with poor perfusion as share of pediatric CPR events
- Proportion of events
- 56.4%
Original publication
Risk-standardizing hospital rates of survival for pediatric in-hospital CPR events. Resuscitation. Published 17 April 2025. doi:10.
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