Role of patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain: a comprehensive narrative review
Authors' conclusion
Due to lack of a consistent approach to identify responders for SCS therapy, trialing complements patient selection to exclude patients who do not find the therapy helpful and/or intolerant of the SCS system.
Study context
- Population
- Adults receiving spinal cord stimulation (SCS) therapy for chronic non-cancer painreports included
- Participants
- 201 adults
- Comparison
- Randomized controlled trials (RCTs) vs observational studies (OSs)
- RCTsn = 36
- OSsn = 41
- Outcome
- Influence of patient variables and trialing on long-term therapy success
Methodological detailscomprehensive, any study design, Medline, EMBASE and Cochrane searched from inception until March 30, 2022, 7321 citations; 60 systematic reviews, 36 RCTs, 41 OSs, 51 registry-based reports, 13 case reports on trialing complications
- Comprehensive
- Any study design
- Medline, EMBASE and Cochrane searched from inception until March 30, 2022
- 7321 citations; 60 systematic reviews, 36 RCTs, 41 OSs, 51 registry-based reports, 13 case reports on trialing complications
Main finding
As reported in the abstract
Trial success rate and therapy success · 12 months
Trial success rate and therapy success · 12 months RCTs median 72% · OSs median 82%
Therapy success at 12 months
Further findings
Trial duration
Original publication
Role of patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain: a comprehensive narrative review. Reg Anesth Pain Med. Published 30 March 2023. doi:10.
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