Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Amer, M; Alshahrani, MS; Arabi, YM; Al-Jedai, A; Alshaqaq, HM; Al-Sharydah, A; Al-Suwaidan, FA; Aljehani, H; Nouh, T; Mashbari, H; Tarazan, N; Alqahtani, S; Tashkandi, W; Maghrabi, K; Albugami, M; Hashim, S; Alsubaie, NM; Alsenani, M; Algethamy, H; Alshammari, TM; Alaklabi, A; Ismail, N; Altawil, ES; Elhazmi, A; Nahhas, A; Aljuaid, M; Alsadoon, N; Binbraik, Y; Yuan, Y; Alhazzani, W

doi:10.1186/s13613-023-01135-8

Trauma & major bleeding

Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Ann Intensive CarePublished 11 May 2023Clinical practice guideline

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Cite

Methodological detailsGRADE approach, evidence-to-decision framework, 22 multidisciplinary panel members; meta-analyses conducted or updated; GRADE used for quality of evidence

GRADE approach
Evidence-to-decision framework
22 multidisciplinary panel members; meta-analyses conducted or updated; GRADE used for quality of evidence

Recommendations

As issued by the authors

weak
Start early pharmacologic venous thromboembolism (VTE) prophylaxis for non-operative blunt solid organ injuries, isolated blunt traumatic brain injury (TBIs) and spinal cord injury (SCIs)
weak
Use low molecular weight heparin (LMWH) over unfractionated heparin (UFH)
weak
Either intermediate-high dose LMWH or conventional dosing LMWH
strong
Mechanical VTE prophylaxis with intermittent pneumatic compression (IPC) in adults with trauma who are not pharmacologic candidates
weak
Either combined mechanical and pharmacologic VTE prophylaxis or pharmacologic VTE prophylaxis alone
weak
Routine bilateral lower extremity ultrasonography (US) in adults with trauma with elevated VTE risk ineligible for pharmacologic VTE prophylaxis
weak
Against routine placement of prophylactic inferior vena cava filters (IVCFs)
no recommendation
Early pharmacologic VTE prophylaxis in isolated blunt TBI requiring neurosurgical intervention (insufficient evidence)

Reference

Issued by: Saudi Critical Care Society (SCCS); endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine
Document: Clinical practice guidelines
Scope: VTE prevention in adults with trauma in inpatient settings; 12 recommendations (1 strong, 10 weak, 1 no recommendation)

Authors: Amer M, Alshahrani MS, Arabi YM, Al-Jedai A, Alshaqaq HM, Al-Sharydah A, et al.
All 30 authors
Amer M, Alshahrani MS, Arabi YM, Al-Jedai A, Alshaqaq HM, Al-Sharydah A, Al-Suwaidan FA, Aljehani H, Nouh T, Mashbari H, Tarazan N, Alqahtani S, Tashkandi W, Maghrabi K, Albugami M, Hashim S, Alsubaie NM, Alsenani M, Algethamy H, Alshammari TM, Alaklabi A, Ismail N, Altawil ES, Elhazmi A, Nahhas A, Aljuaid M, Alsadoon N, Binbraik Y, Yuan Y, Alhazzani W
Journal: Annals of Intensive Care
Published: 11 May 2023
DOI: 10.1186/s13613-023-01135-8
PubMed: 37165105

Topic: Trauma & major bleeding

Original publication

Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine. Ann Intensive Care. Published 11 May 2023. doi:10.1186/s13613-023-01135-8

Read the original article ↗

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