Cardiac arrest & resuscitation
Sex- and Age-Based Disparities in Public Access Defibrillation, Bystander Cardiopulmonary Resuscitation, and Neurological Outcome in Cardiac Arrest
Main finding · Favorable neurological outcome, younger females vs males of same ageResult — go to the resultOdds ratio 1.19 95% CI 1.08–1.31Authors' conclusion
Results of this study suggest a pattern of significant sex- and age-based differences in bystander CPR, public access defibrillation, and neurological outcomes in Japan.
Study context
- Population
- Patients with out-of-hospital cardiac arrest (OHCA) of cardiac origin witnessed by citizens and treated by EMS personnel, All-Japan Utstein Registry, 2005–2020median age 78 years
- Participants
- 354,409 patients
- Exposure
- Females vs males, stratified by age
- Femalesn = 136,520
- Outcome
- Favorable neurological outcome (Cerebral Performance Category 1 or 2)
- Follow-up
- 30 days
Methodological detailspopulation-based, nationwide registry
- Population-based
- Nationwide registry
Main finding
As reported in the abstract
Favorable neurological outcome, younger females vs males of same age
Odds ratio
1.19
95% CI 1.08–1.31
Females vs Males
OR 1.19 (95% CI 1.08–1.31)
Observational data: associations, not effects.
Secondary outcomes
Public access defibrillation
P < 0.001
Favorable neurological outcome by intervention (younger females, nonfamily-witnessed OHCA subgroup)
| OR (95% CI) | ||
|---|---|---|
| Public access defibrillation | 3.51 (2.34–5.27) | |
| Bystander CPR | 1.62 (1.20–2.22) | |
| 0.20.5125Odds ratio (log scale) |
Public access defibrillation and bystander cardiopulmonary resuscitation (CPR) (younger patients)
- Younger females had a lower rate of public access defibrillation and bystander CPR than males
Original publication
Sex- and Age-Based Disparities in Public Access Defibrillation, Bystander Cardiopulmonary Resuscitation, and Neurological Outcome in Cardiac Arrest. JAMA Netw Open. Published 3 July 2023. doi:10. 1001/ jamanetworkopen. 2023. 21783
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