Cardiac arrest & resuscitation

Standardisation facilitates reliable interpretation of end-tidal CO2 (ETCO2) during manual cardiopulmonary resuscitation

ResuscitationPublished Retrospective cohort study

Authors' conclusion

Standardising ETCO2 eliminates effects of VR and CD variations during manual CPR and facilitates comparison of values and trends among and within patients.

Study context

Population
OHCA cases with manual cardiopulmonary resuscitation (CPR)of 1,036 cases
Participants
287 cases
Exposure
Standardised ETCO2 vs measured ETCO2
Outcome
ETCO2 values and trends during resuscitation

Main finding

As reported in the abstract

Ventilation rate (VR) mostly lower than recommended, highly variable within and among patients

8.8 vpm

Compression depth (CD) mostly within guidelines, less varied

49.8 mm

ETs lower than ETm

7.3 mmHg

Observational data: associations, not effects.

Further findings

OutcomeValues
ETs by sexFemales 22.4 mmHg · Males 25.6 mmHg
ETs by initial rhythmShockable 29.1 mmHg · Not shockable 22.7 mmHg
ETs by intubation typeSupraglottic 25.6 mmHg · Endotracheal 22.4 mmHg
ETs by ROSC achievedROSC 34.5 mmHg · No ROSC 20.1 mmHg
ETs trend before ROSCNon-ROSC −0.3 mmHg/min · ROSC + 0.2 mmHg/min
ETs trend after ROSCSustained −0.7 mmHg/min · Rearrest −2.1 mmHg/min
Peak ETsSustained 53.0 mmHg · Rearrest 42.5 mmHg

Original publication

Standardisation facilitates reliable interpretation of ETCO2 during manual cardiopulmonary resuscitation. Resuscitation. Published 31 May 2024. doi:10.1016/j.resuscitation.2024.110259

Composed by AI from the published abstract and checked against it. How Briefs are made →

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