Neuroanesthesia & neurocritical care

Temporal changes and predictors of perioperative blood transfusion in elective spine surgery: a retrospective analysis of a large surgical database

Br J AnaesthPublished Retrospective cohort study

Authors' conclusion

Perioperative blood transfusion rate in spine surgery has declined over the past decade. The extent and duration of surgery and preoperative haemoglobin level remain important factors associated with increased odds for perioperative blood transfusion.

Study context

Population
US inpatients undergoing elective spine surgery, National Surgical Quality Improvement Program (NSQIP) 2011–2019
Participants
251,971 inpatients
Outcome
Perioperative transfusion
Follow-up
Within 72 h of surgery
Methodological detailsNSQIP database, multivariable logistic regression, recursive partitioning
  • NSQIP database
  • Multivariable logistic regression
  • Recursive partitioning

Main finding

As reported in the abstract

Perioperative blood transfusion

Patients receiving perioperative transfusion

6.9%

Observational data: associations, not effects.

Further findings

OutcomeAUC (95% CI)
Predictive model (reduced model, 8 variables: operative time, preoperative haemoglobin, vertebral level, number of vertebral levels, older age, surgeon specialty, arthrodesis, year of surgery)0.880 (0.878–0.883)

Transfusion rate in orthopaedic cases, 2011 to 2015

Declined from 16.0% to 8.7%

Predictive model (reduced model, 8 variables: operative time, preoperative haemoglobin, vertebral level, number of vertebral levels, older age, surgeon specialty, arthrodesis, year of surgery)

Longer operative time (>144 min) and more vertebral levels more strongly associated with transfusion than surgical specialty after adjustment

Prevalence of anaemia

Anaemia prevalence, not substantially declined
15%

Original publication

Temporal changes and predictors of perioperative blood transfusion in elective spine surgery: a retrospective analysis of a large surgical database. Br J Anaesth. Published 30 December 2022. doi:10.1016/j.bja.2022.11.020

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