Cardiac arrest & resuscitation
Termination of resuscitation in out-of-hospital cardiac arrest in women and men: An ESCAPE-NET project
Authors' conclusion
For both women and men, the ALS-TOR has high specificity and low miss rate for predicting 30-day OHCA survival. We could not improve the classification with additional characteristics.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) patients from Dutch and Swedish registries; validation in Danish OHCA patientsvalidation: 10,772 women, 21,808 men
- Participants
- 6,931 vs 14,548
- Comparison
- ALS-TOR rule vs recursive partitioning classification vs simplified rule, in women and men
- Womenn = 6,931
- Menn = 14,548
- Outcome
- Performance of ALS-TOR for predicting 30-day survival
- Follow-up
- 30 days
Methodological detailsregistry-based, external validation
- Registry-based
- External validation
Performance
As reported in the abstract
ALS-TOR performance for 30-day survival
| Test or model | Specificity | PPV |
|---|---|---|
| Women | ≥99% | ≥99% |
| Men | ≥99% | 99.9 |
Specificity
Women≥99%
Men≥99%
PPV
Women≥99%
Men99.9
Further findings
Recursive partitioning classification
- High sensitivity but PPV below 99%, exceeding acceptable miss rate of 1%
Simplified rule (no return of spontaneous circulation (ROSC) before transport + unwitnessed OHCA)
- Nearly equal specificity and PPV, higher sensitivity, lower transport rate vs ALS-TOR
Original publication
Termination of resuscitation in out-of-hospital cardiac arrest in women and men: An ESCAPE-NET project. Resuscitation. Published 13 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →