Cardiac arrest & resuscitation
Termination of Resuscitation Rules and Survival Among Patients With Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis
Authors' conclusion
In this review, there was insufficient robust evidence to support widespread implementation of TOR rules in clinical practice.
Study context
- Population
- Patients with out-of-hospital cardiac arrest (OHCA); prehospital termination of resuscitation (TOR) rules predicting death
- Participants
- 1,125,587 patients · 43 nonrandomized studies
- Outcome
- Sensitivity and specificity of TOR rules (with 95% CIs) and bivariate summary receiver operating characteristic (SROC) curves
Methodological detailsbivariate random-effects meta-analysis, PRISMA-DTA
- Bivariate random-effects meta-analysis
- PRISMA-DTA
Pooled result
As reported in the abstract
Accuracy of the best-performing TOR rule
| Group | Pooled sensitivity | Pooled specificity | Diagnostic OR |
|---|---|---|---|
| Universal TOR rule | 0.62 (95% CI, 0.54-0.71) | 0.88 (95% CI, 0.82-0.94) | 20.45 (95% CI, 13.15-31.83) |
Universal TOR rule
Pooled sensitivity0.62 (95% CI, 0.54-0.71)
Pooled specificity0.88 (95% CI, 0.82-0.94)
Diagnostic OR20.45 (95% CI, 13.15-31.83)
Original publication
Termination of Resuscitation Rules and Survival Among Patients With Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis. JAMA Netw Open. Published 1 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →