Obstetric anesthesia

The Association of the COVID-19 Pandemic With Disparities in Maternal Outcomes

Anesth AnalgPublished Retrospective cohort study

Authors' conclusion

In this national study of 2.5 million deliveries in the United States, the COVID-19 pandemic was associated with increases in maternal mortality and failure-to-rescue but not in severe maternal morbidity or cesarean deliveries.

Study context

Population
US admissions for delivery, Vizient Clinical Database, 2017–2022
Exposure
Weekly hospital COVID-19 burden; Black and Hispanic vs White patients
Outcome
Maternal outcomes (severe maternal morbidity, mortality, failure-to-rescue, cesarean delivery) by weekly hospital COVID-19 burden
Methodological detailsmultivariable logistic regression, national database (Vizient Clinical Database)
  • Multivariable logistic regression
  • National database (Vizient Clinical Database)

Main finding

As reported in the abstract

Maternal outcomes by weekly hospital COVID-19 burden 10.1% to 20.0%
Estimate (95% CI)P value
COVID-19 burden 10.1% to 20.0%
aOR (mortality) 2.72(1.28–5.8)
P = 0.01
COVID-19 burden 10.1% to 20.0%
aOR (failure-to-rescue) 2.89(1.36–6.13)
P = 0.01

Observational data: associations, not effects.

Further findings

OutcomeEstimateP value
Severe maternal morbidity, Black and Hispanic vs WhiteBlack vs WhiteOR 1.97 (95% CI 1.85–2.11)P < 0.001
Severe maternal morbidity, Black and Hispanic vs WhiteHispanic vs WhiteOR 1.37 (95% CI 1.28–1.48)P < 0.001
Mortality, Black and Hispanic vs WhiteBlack vs WhiteOR 1.92 (95% CI 1.29–2.86)P < 0.001
Mortality, Black and Hispanic vs WhiteHispanic vs WhiteOR 1.51 (95% CI 1.01–2.24)P = 0.04
Cesarean delivery, Black and Hispanic vs WhiteBlack vs WhiteOR 1.58 (95% CI 1.54–1.63)P < 0.001
Cesarean delivery, Black and Hispanic vs WhiteHispanic vs WhiteOR 1.09 (95% CI 1.05–1.13)P < 0.001
Pandemic and disparities: uninsured Black vs privately insured White, per 10% increase in weekly hospital COVID-19 burden (subgroup)Black without insurance vs White with private insuranceaOR (mortality) 1.96 (95% CI 1.22–3.16)P = 0.01
Pandemic and disparities: uninsured Black vs privately insured White, per 10% increase in weekly hospital COVID-19 burden (subgroup)Black without insurance vs White with private insuranceaOR (failure-to-rescue) 3.67 (95% CI 1.67–8.07)P = 0.001

Cesarean delivery, Black and Hispanic vs White

Failure-to-rescue not higher in Black or Hispanic patients

Pandemic and disparities: uninsured Black vs privately insured White, per 10% increase in weekly hospital COVID-19 burden (subgroup)

Except for uninsured Black patients (1.3% of patients), pandemic not associated with increased maternal disparities

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The Association of the COVID-19 Pandemic With Disparities in Maternal Outcomes. Anesth Analg. Published 22 January 2025. doi:10.1213/ane.0000000000007323

Composed by AI from the published abstract and checked against it. How Briefs are made →

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