Pediatric anesthesia & critical care
The Effects of Intraoperative Methadone on Postoperative Pain Control in Pediatric Patients: A Scoping Review
Authors' conclusion
Although the data reviewed highlight a potential benefit of intraoperative methadone in pediatric patients, 4 of the 5 studies had serious methodological concerns.
Study context
- Population
- Pediatric patients undergoing surgery5 studies
- Comparison
- Intraoperative methadone vs other opioids
- Outcome
- Postoperative opioid consumption, pain scores and adverse events
Methodological details1864 studies screened, 83 full-text reviewed, 4 of the 5 studies had serious methodological concerns, PubMed, Scopus, Embase and Cumulative Index to Nursing and Allied Health Literature (CINAHL) searched from inception to January 2023
- 1864 studies screened, 83 full-text reviewed
- 4 of the 5 studies had serious methodological concerns
- PubMed, Scopus, Embase and CINAHL searched from inception to January 2023
Main finding
As reported in the abstract
Postoperative opioid consumption
- Postoperative opioid consumption decreased overall with methadone vs no methadone
- Most studies indicated methadone superior to other opioids in pain scores
Safety
- Frequency of adverse events similar between groups
Original publication
The Effects of Intraoperative Methadone on Postoperative Pain Control in Pediatric Patients: A Scoping Review. Anesth Analg. Published 7 June 2024. doi:10.
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